Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish
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منابع مشابه
Ptenb Mediates Gastrulation Cell Movements via Cdc42/AKT1 in Zebrafish
Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP(2)/PIP(3) balance. Although PI3 kinase counter enzyme PTEN has also been reported to be essential for gastrulation, its role in zebrafish gastrulation has been controversial due to the lack of gastrulation defects in pten-null mutants. To clarify this issue, we knocked down a p...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0018702